How to Write a Synthesis Essay: Effective Tips and Tricks.
Solithromycin is a novel ketolide antibiotic. Solithromycin (CAS 760981-83-7) can be used for anti-infection, and It is expected to be the first macrolide antibiotic available in intravenous, oral, and pediatric suspension formulations in over 20 years.
Oral solithromycin will be given as an 800mg loading dose on the first day o followed by 400mg once daily for 7 days; moxifloxacin will be given as 400mg once daily for 7 days. The primary outcome is non-inferiority in the early clinical response rates. ECR is defined as improvement at 72 hours after the first dose of study medication (3) Dec 12: Company announce the start of a global PIII.
Solithromycin (CEM-101 and OP-1068) Solithromycin (Cempra Pharmaceuticals, Chapel Hill, NC) is a novel fluoroketolide, a fourth-generation macrolide agent demonstrating activity against pathogens resistant to earlier-generation macrolides, such as erythromycin and azithromycin.
FIG 1 Inhibition of protein synthesis rate, growth rate, and CFU by solithromycin for S. pneumoniae (a), methicillin-susceptible S. aureus (MSSA) (b), methicillin-resistant S. aureus (MRSA) (c).
Stereochemistry of Solithromycin is wrong. Hello, I don't know how to exchange the picture, but I think the stereochemistry of solithromycin is wrong. Please check the methyl group opposite to the lactone. — Preceding unsigned comment added by 18.104.22.168 14:12, 13 June 2018 (UTC) I believe you are right. I have uploaded a corrected image.
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